Division of Trauma Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. anne
Int Wound J. 2010 Dec;7(6):467-71. doi: 10.1111/j.1742-481X.2010.00718.x. Epub 2010 Sep 21.
Askina Calgitrol Ag(®) (B. Braun Hospicare Ltd, Collooney Co. Sligo, Ireland), alginate silver wound dressing, is an advanced wound dressing which combines the potent broad-spectrum antimicrobial action of silver with enhanced exudate management properties of calcium alginate and polyurethane foam. The purpose of this study was to compare the efficacy of Askina Calgitrol Ag(®) and 1% silver sulfadiazine (1% AgSD) in the outpatient management of partial-thickness burn wounds at Burn Unit, Siriraj Hospital. A prospective descriptive study was conducted between January 2008 and January 2009 in Burn Unit, Division of Trauma Surgery, Siriraj Hospital, Mahidol University, Thailand. The 65 patients with partial-thickness burn wounds, less than 24 hours post-burn injury, had a total body surface area (TBSA%) less than 15% were treated at Siriraj Outpatient Burn Clinic. All patients were divided into Askina Calgitrol Ag(®) treated group (30 patients) and 1% AgSD treated group (35 patients). The data were compared by the demographics including age, gender, % TBSA burn, pain score, number of wound dressing change, nursing time and time of wound healing. Patients included in both groups were comparable with no significant differences in demographic data of age, gender, location of burn and type of burn injury (P > 0·05 evaluated by paired Student's t-test) between both group. The present results showed that average pain scores in the Askina Calgitrol Ag(®) treated group were significantly lower than the 1% AgSD treated group (2·23 ± 1·87 versus 6·08 ± 2·33, respectively) between both groups (P < 0·02). Patients treated with Askina Calgitrol Ag(®) had significantly lower number of wound dressing change (P < 0·02) and nursing time (P < 0·02) compared with 1% AgSD treated group. The Askina Calgitrol Ag(®) group needed less frequent wound dressing. Healing time was 7 ± 3·51 days after the application of Askina Calgitrol Ag(®). This was significantly shorter than that of control wounds (14 ± 4·18 days). Application of Askina Calgitrol Ag(®) leads to a good burn wound outcome. The present study confirms the effectiveness of Askina Calgitrol Ag(®) in the outpatient management of partial-thickness burn wounds.
安可赛银藻酸盐伤口敷贴(®)(B. Braun Hospicare Ltd,爱尔兰斯莱戈郡科洛尼)是一种高级伤口敷贴,它将银的广谱强效抗菌作用与藻酸钙和聚氨酯泡沫的增强渗出物管理特性相结合。本研究旨在比较安可赛银藻酸盐(®)和 1%磺胺嘧啶银(1% AgSD)在烧伤科门诊治疗部分厚度烧伤创面的疗效。这是一项在泰国玛希隆大学 Siriraj 医院创伤外科烧伤科进行的 2008 年 1 月至 2009 年 1 月期间的前瞻性描述性研究。共有 65 名烧伤面积小于 24 小时的部分厚度烧伤患者,烧伤总面积(TBSA%)小于 15%,在 Siriraj 门诊烧伤诊所接受治疗。所有患者均分为安可赛银藻酸盐(®)治疗组(30 例)和 1% AgSD 治疗组(35 例)。通过年龄、性别、烧伤 TBSA%、疼痛评分、伤口换药次数、护理时间和伤口愈合时间等人口统计学数据进行比较。两组患者在年龄、性别、烧伤部位和烧伤类型(配对学生 t 检验,P > 0.05)等人口统计学数据方面无显著差异。结果表明,安可赛银藻酸盐(®)治疗组的平均疼痛评分明显低于 1% AgSD 治疗组(分别为 2.23 ± 1.87 与 6.08 ± 2.33,P < 0.02)。与 1% AgSD 治疗组相比,安可赛银藻酸盐(®)治疗组的伤口换药次数(P < 0.02)和护理时间(P < 0.02)明显减少。安可赛银藻酸盐(®)组需要更频繁的伤口换药。应用安可赛银藻酸盐(®)后,创面愈合时间为 7 ± 3.51 天。这明显短于对照组(14 ± 4.18 天)。应用安可赛银藻酸盐(®)可获得良好的烧伤创面效果。本研究证实了安可赛银藻酸盐(®)在门诊治疗部分厚度烧伤创面的有效性。