CHU de Brest, hôpital Morvan, France.
Eur Ann Otorhinolaryngol Head Neck Dis. 2010 Sep;127(4):130-6. doi: 10.1016/j.anorl.2010.07.004.
To develop a graph of semi-quantitative Biolfa(®) olfactory test data and to assess a method of mathematical measurement of the gap between odor perception and identification thresholds.
The semi-quantitative Biolfa(®) olfaction test comprises eight smells, each diluted in four increasing concentrations. Perception and identification threshold data for 158 patients was displayed in a radar-like diagram. The gap between odor perception threshold and odor identification threshold was quantified as the area between the perception and identification threshold curves.
The gap calculated between odor perception and identification thresholds differentiated between etiologic origins of olfactory disorders. In cm², the gap ranged from 0 to 82.73 cm². Low values indicated a peripheral origin, and high values a central origin for olfactory disorders (p>0.05). On the other hand, no olfactory profile specific to each of the main etiologies responsible for olfactory disorder was found to exist.
This radar-like graphic display of semi-quantitative Biolfa(®) olfactory test data is a simple means of providing an overall view of the data. Studying the gap between perception and identification thresholds for smells is relevant for diagnosis of central olfactory disorders.
开发 Biolfa(®)嗅觉测试半定量数据图,并评估一种用于测量气味感知和识别阈值之间差距的数学测量方法。
Biolfa(®)嗅觉测试包括八种气味,每种气味均以四种递增浓度稀释。158 名患者的感知和识别阈值数据显示在类似雷达的图表中。气味感知阈值和气味识别阈值之间的差距通过感知和识别阈值曲线之间的区域来量化。
计算出的嗅觉感知和识别阈值之间的差距区分了嗅觉障碍的病因起源。以平方厘米为单位,差距范围为 0 至 82.73 平方厘米。低值表示嗅觉障碍的外周起源,高值表示嗅觉障碍的中枢起源(p>0.05)。另一方面,没有发现特定于导致嗅觉障碍的主要病因之一的特定嗅觉特征。
这种 Biolfa(®)嗅觉测试半定量数据的类似雷达图形显示是提供数据整体视图的一种简单方法。研究气味感知和识别阈值之间的差距对于诊断中枢嗅觉障碍具有重要意义。