Unidade de Microbiologia e Biologia Molecular, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, 2350 Ramiro Barcelos Street, Porto Alegre 90035-903, RS, Brazil.
J Clin Microbiol. 2010 Dec;48(12):4652-4. doi: 10.1128/JCM.01182-10. Epub 2010 Sep 22.
Vancomycin MIC results were determined by the broth microdilution (BMD) method and by Etest using 130 methicillin-resistant coagulase-negative staphylococcus bloodstream isolates obtained from a tertiary hospital. The majority (98.5%) of MIC results determined by BMD were ≤1 μg/ml, in contrast to MIC results determined by Etest (72.3% were ≥1.5 μg/ml). The MICs obtained by Etest were, in general, 1- to 2-fold higher than the MICs obtained by BMD.
万古霉素 MIC 结果采用肉汤微量稀释（BMD）法和 Etest 法测定，共检测了从一家三级医院获得的 130 株耐甲氧西林凝固酶阴性葡萄球菌血流感染分离株。BMD 法测定的 MIC 结果中，绝大多数（98.5%）为≤1μg/ml，而 Etest 法测定的 MIC 结果（72.3%）为≥1.5μg/ml。Etest 法测定的 MIC 一般比 BMD 法测定的 MIC 高 1-2 倍。
