Mitchell Amy, Smith Howard S
Albany Medical Center, New York, USA.
J Opioid Manag. 2010 Jul-Aug;6(4):290-4. doi: 10.5055/jom.2010.0026.
Fentanyl transdermal patches (FTPs) have been used for many years in the treatment armamentarium for chronic pain. By design, FTPs release drug into the skin at a constant rate and thereby provide drug in a fashion similar to continuous intravenous infusion without the disadvantages of a venous catheter and the constant presence of an analgesia pump. Pediatric patients may require doses of FTP other than the five commercially available strengths. Application of a partial FTP allows for more flexibility in dosing. Yet, very little information is provided in the literature to suggest a procedure for applying partial FTP. A technique of using a partially occluded FTP is presented in an effort to encourage further study of this and perhaps other techniques.
芬太尼透皮贴剂（FTPs）多年来一直用于慢性疼痛的治疗手段中。从设计上来说，FTPs以恒定速率将药物释放到皮肤中，从而以类似于持续静脉输注的方式提供药物，而没有静脉导管和镇痛泵持续存在的缺点。儿科患者可能需要除了五种市售强度之外的FTP剂量。应用部分FTP在给药方面具有更大的灵活性。然而，文献中提供的信息极少，无法表明应用部分FTP的程序。本文介绍了一种使用部分封闭的FTP的技术，以期鼓励对该技术以及可能的其他技术进行进一步研究。
