Zhang Lianjun, Lu Jin, Le Kang, Fu Tingming, Guo Liwei
Key Laboratory of Separation Engineering for Chinese Medicine Compound, Nanjing University of Chinese Medicine, Nanjing 210029, China.
Zhongguo Zhong Yao Za Zhi. 2010 Jul;35(13):1691-5. doi: 10.4268/cjcmm20101308.
To investigate the effect of differents solution environments on the ceramic membrane microfiltration of model system of Chinese medicines.
Taking binary system of soybean protein-berberine as the research object, flux, transmittance of berberine and traping rate of protein as indexes, different solution environment on membrane process were investigated.
When the concentration of soybean protein was under 1 g x L(-1), the membrane flux was minimum with the traping of berberine decreased slightly as the concentration increased. When pH was 4, the flux was maximum with the traping rate of protein was 99%, and the transmittance of berberine reached above 60%.
The efficiency of membrane separation can be improved by optimizing the solution environment of water-extraction of chinese medicines. The efficiency of membrane separation is the best when adjust the pH to the isoelectric point of proteins for the proteins as the main pollutant in aqueous solution.
研究不同溶液环境对中药模型体系陶瓷膜微滤的影响。
以大豆蛋白 - 小檗碱二元体系为研究对象，以通量、小檗碱透过率和蛋白质截留率为指标，考察不同溶液环境对膜过程的影响。
当大豆蛋白浓度低于1 g·L⁻¹时，膜通量最小，随着浓度增加，小檗碱截留率略有下降。当pH为4时，通量最大，蛋白质截留率为99%，小檗碱透过率达到60%以上。
通过优化中药水提液的溶液环境可提高膜分离效率。当将水溶液中以蛋白质为主要污染物的pH调节至蛋白质的等电点时，膜分离效率最佳。
