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Regional brain cortical thinning and systemic inflammation in older persons without dementia.

作者信息

Fleischman Debra A, Arfanakis Konstantinos, Kelly Jeremiah F, Rajendran Niranjini, Buchman Aron S, Morris Martha C, Barnes Lisa L, Bennett David A

出版信息

J Am Geriatr Soc. 2010 Sep;58(9):1823-5. doi: 10.1111/j.1532-5415.2010.03049.x.

DOI:10.1111/j.1532-5415.2010.03049.x
PMID:20863359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2945260/
Abstract
摘要

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2
The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals.阿尔茨海默病的皮质特征：在极轻度至轻度AD痴呆中，区域特异性皮质变薄与症状严重程度相关，且在无症状淀粉样蛋白阳性个体中可检测到。
Cereb Cortex. 2009 Mar;19(3):497-510. doi: 10.1093/cercor/bhn113. Epub 2008 Jul 16.
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Biol Psychiatry. 2008 Sep 15;64(6):484-90. doi: 10.1016/j.biopsych.2008.04.016. Epub 2008 Jun 2.
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