Reim H, Dieler R, Wessing A
Augenklinik, Medizinischen Fakultät der RWTH, Aachen, Bundesrepublik Deutschland.
Fortschr Ophthalmol. 1990;87(6):557-9.
Lymphoma affecting the eye is a special form of Non-Hodgkin's Lymphoma, which was formerly described as reticulum cell sarcoma and is now mostly identified as highly malignant lymphoma. The clinical findings include posterior uveitis with dense opacities of the vitreous body. We present two female patients with minor opacities of the vitreous body, thus permitting funduscopic inspection and leading to the diagnosis of chorioretinitis. Fundus examination of the first patient revealed confluent infiltrates in both eyes. She developed progressive neurological symptoms within 10 weeks and died of respiratory insufficiency. All parenchymatous organs and the central and peripheral nervous system showed multifocal infiltration with cells deriving from a malignant T-cell lymphoma. The second patient presented with subretinal infiltration surrounding the right optic nerve head. Over the following weeks the infiltrations first spread towards the temporal fundus and then disappeared spontaneously, forming scars with atrophy of the pigment epithelium.
累及眼部的淋巴瘤是非霍奇金淋巴瘤的一种特殊形式，以前被描述为网状细胞肉瘤，现在大多被认定为高度恶性淋巴瘤。临床症状包括伴有玻璃体致密混浊的后葡萄膜炎。我们报告两名女性患者，她们的玻璃体有轻微混浊，从而能够进行眼底检查并诊断为脉络膜视网膜炎。对第一名患者的眼底检查发现双眼有融合性浸润。她在10周内出现进行性神经症状，死于呼吸功能不全。所有实质器官以及中枢和周围神经系统均显示有源自恶性T细胞淋巴瘤的细胞多灶性浸润。第二名患者表现为围绕右侧视神经乳头的视网膜下浸润。在接下来的几周里，浸润首先向颞侧眼底扩散，然后自发消失，形成伴有色素上皮萎缩的瘢痕。
