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视网膜“原发性”网状细胞肉瘤。II. 放疗后的临床诊断及病程(作者译)

["Primary" reticulum cell sarcoma of the retina. II. Clinical diagnosis and course after radiotherapy (author's transl)].

作者信息

Naumann G O, Völcker H E

出版信息

Klin Monbl Augenheilkd. 1977 Oct;171(4):499-506.

PMID:338965
Abstract

A 59-year-old patient with "exudative chorioretinitis" progressed from confluent infiltration of the deep layers of the sensory retina, perivascularly and at the level of the pigmentepithelium to total infiltration of the vitreous. This occurred in spite of all the conventional antiinflammatory therapy. A clinical diagnosis of primary reticulum-cellsarcoma of the retina was made because diagnostic vitrectomy for cytologic study was refused. Radiotherapy with 4000 R by Betatron led to a rapid disappearance of the infiltration in the vitreous and retina and to diffuse subretinal scaring of the entire fundus (histologically confirmed). One year later the patient died in a psychiatrically disoriented state. It is thought that the course after radiotherapy and the histological findings support, although not definitely confirm, the clinical diagnosis. Clinical criteria may suffice for the diagnosis in desperate situations to initiate effective radiotherapy in these fatally ill patients.

摘要

一名59岁患有“渗出性脉络膜视网膜炎”的患者,病变从感觉视网膜深层、血管周围及色素上皮层的融合浸润发展至玻璃体完全浸润。尽管进行了所有常规抗炎治疗,病情仍如此发展。由于患者拒绝进行用于细胞学研究的诊断性玻璃体切除术,故临床诊断为原发性视网膜网状细胞肉瘤。使用电子感应加速器进行4000伦琴的放射治疗后,玻璃体和视网膜的浸润迅速消失,整个眼底出现弥漫性视网膜下瘢痕形成(经组织学证实)。一年后,患者在精神错乱状态下死亡。据认为,放射治疗后的病程及组织学检查结果虽不能明确证实,但支持了临床诊断。在绝望的情况下,临床标准可能足以用于诊断,以便在这些重症患者中启动有效的放射治疗。

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