Brummer-Korvenkontio H, Lappalainen P, Reunala T, Palosuo T
National Public Health Institute, Helsinki, Finland.
Int Arch Allergy Appl Immunol. 1990;93(1):14-8. doi: 10.1159/000235273.
Rabbits immunized with 50-60 Aedes communis mosquito bites developed IgG antibodies recognizing a 21.5-kD mosquito antigen detected by the immunoblot technique. This protein seems to be a major immunogen in the saliva of A. communis mosquitoes. Studies on 60 human sera revealed that IgG antibodies recognizing the 21.5-kD antigen occurred in about 50% of young children and adults but were not found in the sera of 20 unexposed infants. The present immunoblot method allows further characterization of antigens and antibodies specific to mosquito saliva and contributes to understanding their role in mosquito bite reactions.
用50 - 60次普通伊蚊叮咬免疫的兔子产生了IgG抗体，该抗体可识别通过免疫印迹技术检测到的一种21.5-kD的蚊子抗原。这种蛋白质似乎是普通伊蚊唾液中的主要免疫原。对60份人类血清的研究表明，识别21.5-kD抗原的IgG抗体在约50%的幼儿和成人血清中出现，但在20名未接触过的婴儿血清中未发现。目前的免疫印迹方法有助于进一步鉴定蚊子唾液特有的抗原和抗体，并有助于了解它们在蚊虫叮咬反应中的作用。
