National Institute of Cholera and Enteric Diseases, Kolkata, India.
Bull World Health Organ. 2010 Sep 1;88(9):667-74. doi: 10.2471/BLT.09.073742. Epub 2010 May 21.
To define mortality patterns in an urban slum in Kolkata, India, in the context of a cholera and typhoid fever project.
In a well-defined population that was under surveillance for 18 months, we followed a dynamic cohort of 63 788 residents whose households were visited monthly by community health workers to identify deaths. Trained physicians performed verbal autopsies and experienced senior physicians assigned the primary cause of death according to the International classification of diseases, 10th edition. We tabulated causes of death in accordance with Global Burden of Disease 2000 categories and assessed overall and cause-specific mortality rates per age group and gender.
During 87 921 person-years of follow-up, we recorded 544 deaths. This gave an overall mortality rate of 6.2 per 1000 person-years. We assigned a cause to 89% (482/544) of the deaths. The leading causes of death, in descending order, were cardiovascular diseases (especially among adults aged over 40 years), cancer, respiratory ailments and digestive disorders. Most deaths in children under 5 years of age were caused by tuberculosis, respiratory infections and diarrhoeal diseases.
Although the most common causes of death in children were infectious, non-communicable diseases were predominant among adults. There is a need for continuing interventions against infectious diseases in addition to new and innovative strategies to combat non-infectious conditions.
在印度加尔各答的一个城市贫民窟中,在霍乱和伤寒项目的背景下,确定死亡率模式。
在一个经过明确界定的、有 18 个月监测期的人群中,我们对一个动态队列进行了随访,该队列包括 63788 名居民,其家庭每月都有社区卫生工作者上门访视以识别死亡。受过训练的医生进行口头尸检,经验丰富的高级医生根据国际疾病分类第 10 版确定主要死因。我们根据 2000 年全球疾病负担分类对死因进行了分类,并评估了各年龄组和性别的总死亡率和死因特异性死亡率。
在 87921 人年的随访期间,我们记录了 544 例死亡。这使得总死亡率为每 1000 人年 6.2 例。我们对 89%(482/544)的死亡病例确定了死因。死亡率依次为心血管疾病(尤其是 40 岁以上的成年人)、癌症、呼吸疾病和消化系统疾病。5 岁以下儿童的大多数死亡是由结核病、呼吸道感染和腹泻引起的。
尽管儿童最常见的死因是传染病,但成年人中以非传染性疾病为主。除了继续采取针对传染病的干预措施外,还需要制定新的创新策略来应对非传染性疾病。