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肾移植与病毒感染。III. 临床与病毒学相关性。

Renal transplantation and viral infections. III. Clinical and virological correlations.

作者信息

Descamps P, Bedrossian J, Nochy D, Duboust A, Idatte J M, Lagrange P, Acar J, Leroux-Robert C, Sraer J D, Kourilsky O, Meyrier A, Dupuy C A, Huraux J M, Nicolas J C, Bricout F

出版信息

Biomedicine. 1978 May;28(2):113-9.

PMID:208676
Abstract

Studies of the serological development after 26 renal transplants confirm the high frequency of antibody rises not only against the herpes virus group, but also against other virus groups such as measles, Coxsackie B viruses. These antibody rises correlate with febrile episodes and hepatic dysfunction in which CMV is the most often involved. However, the frequency of antibody rises against various viral antigens without any clinical event to suggest viral etiology; the lack of concomitant virus isolation (except the herpes group), as well as the ocurrence of simultaneous antibody rises against several viruses, all suggest that some of these various antibody rises observed may be related to immunological dysfunction rather than to virus infection.

摘要

对26例肾移植术后血清学变化的研究证实,抗体升高不仅在疱疹病毒组中很常见,在其他病毒组如麻疹病毒、柯萨奇B病毒中也很常见。这些抗体升高与发热发作和肝功能障碍相关,其中巨细胞病毒最为常见。然而,在没有任何临床事件提示病毒病因的情况下,针对各种病毒抗原的抗体升高频率;缺乏伴随的病毒分离(疱疹病毒组除外),以及同时出现针对多种病毒的抗体升高,都表明观察到的这些各种抗体升高可能部分与免疫功能障碍有关,而非病毒感染。

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Renal transplantation and viral infections. III. Clinical and virological correlations.肾移植与病毒感染。III. 临床与病毒学相关性。
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引用本文的文献

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Viral immunodiagnosis.病毒免疫诊断
Yale J Biol Med. 1980 Jan-Feb;53(1):71-83.