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肾移植与病毒感染。II. 随访研究结果。

Renal transplantation and viral infections. II. Results of follow-up studies.

作者信息

Huraux J M, Bricout F, Nicolas J C, Regnard J, Bogossian M, Descamps P, Grimfeld A, Gerbal A, Baptista-Lourenco M H

出版信息

Biomedicine. 1975 Jul;22(4):311-9.

PMID:179630
Abstract

13 renal transplant recipeints were submitted to virological survey over a period of about 10 months following transplantation. They were compared to a group of individuals who underwent no transplantation : 7 patients on chronic hemodialysis and 10 healthy blood donors. The renal transplant recipients, showed rises in titer of antibodies against various viral antigens. Nevertheless, no other viral elimination but that of cytomegalovirus and herpes simplex virus was detected in them. Renal trnasplant recipients show significantly more often rises in virus antibody titers than the other individuals, when time of survey is taken into account. Some of these rises appeared to be simultaneous. Their mechanism is under debate : analysis of special cases and observation of associated immunohematological abnormalities are strongly suggesting that in some situations, rises in titer of viral antibodies may occur without infection.

摘要

13名肾移植受者在移植后约10个月的时间里接受了病毒学调查。他们与一组未接受移植的个体进行了比较:7名慢性血液透析患者和10名健康献血者。肾移植受者体内针对各种病毒抗原的抗体滴度有所上升。然而,在他们体内除了检测到巨细胞病毒和单纯疱疹病毒的清除外,未发现其他病毒清除情况。考虑到调查时间,肾移植受者体内病毒抗体滴度升高的情况比其他个体更为常见。其中一些升高似乎是同时发生的。其机制仍在争论中:对特殊病例的分析以及对相关免疫血液学异常情况的观察强烈表明,在某些情况下,病毒抗体滴度的升高可能在没有感染的情况下发生。

相似文献

1
Renal transplantation and viral infections. II. Results of follow-up studies.肾移植与病毒感染。II. 随访研究结果。
Biomedicine. 1975 Jul;22(4):311-9.
2
Renal transplantation and viral infections. III. Clinical and virological correlations.肾移植与病毒感染。III. 临床与病毒学相关性。
Biomedicine. 1978 May;28(2):113-9.
3
Virus infections in renal transplant recipients.
Z Immunitatsforsch Exp Klin Immunol. 1975 Feb;148(4):341-55.
4
[Prevalence of antibodies against herpes simplex virus, Epstein-Barr virus and cytomegalovirus in a group of patients after hemodialysis].[一组血液透析患者中抗单纯疱疹病毒、EB病毒和巨细胞病毒抗体的患病率]
Rev Cubana Med Trop. 1999 Sep-Dec;51(3):172-6.
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[Herpes simplex virus antibodies in 18 patients submitted to immunosuppressive agents after renal transplantation].[18例肾移植后接受免疫抑制剂治疗患者的单纯疱疹病毒抗体]
Pathol Biol (Paris). 1975 May;23(5):371-4.
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CMV infection in patients with chronic renal failure and in those following transplantation.
Czech Med. 1988;11(3):131-6.
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[Sero-epidemiological results in subjects receiving a renal transplant].[接受肾移植患者的血清流行病学结果]
Boll Ist Sieroter Milan. 1985;64(3):240-3.
8
Diagnosis, surveillance, and epidemiologic evaluation of viral infections in pediatric cardiac transplant recipients with the use of the polymerase chain reaction.利用聚合酶链反应对小儿心脏移植受者的病毒感染进行诊断、监测和流行病学评估。
J Heart Lung Transplant. 1996 Feb;15(2):111-23.
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Chlamydia pneumoniae infection and ischemic heart disease in hemodialysis patients.血液透析患者中的肺炎衣原体感染与缺血性心脏病
Transplant Proc. 2006 Jan-Feb;38(1):31-4. doi: 10.1016/j.transproceed.2005.12.033.
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Viral infections in renal transplant donors and their recipients: a prospective study.肾移植供体及其受体中的病毒感染:一项前瞻性研究。
Surgery. 1977 May;81(5):487-92.

引用本文的文献

1
Ophthalmological complications of haemodialysis and kidney transplantation.血液透析和肾移植的眼科并发症
Doc Ophthalmol. 1980 May 30;49(1):v-vii, 1-96. doi: 10.1007/BF00175176.
2
Herpes zoster and acute rejection crisis of renal homograft.
Int Urol Nephrol. 1979;11(4):363-6. doi: 10.1007/BF02086823.