Department of Urology, Takamatsu Red Cross Hospital, Tokushima University, Tokushima, Japan.
BJU Int. 2011 May;107(9):1442-6. doi: 10.1111/j.1464-410X.2010.09644.x. Epub 2010 Sep 24.
• To examine the feasibility of three-dimensional (3D) CT cavernosography in the diagnosis of corporal veno-occlusive dysfunction.
• The subjects were 55 patients who had failed to respond to phosphodiesterase type 5 inhibitors. We performed pharmacodynamic infusion cavernosometry and cavernosography, using 60 mg papaverine hydrochloride. • Cavernosography was performed at 90 mmHg intracavernous pressure, using a multi-slice CT scan system. The 3D images were reconstructed using aquarius net station, ver.2 computer software. • For comparison with conventional cavernosography, maximum intensity projection (MIP) images were used. A flow of 20 mL/min or being more capable of maintaining 90 mmHg of intracavernous pressure indicated veno-occlusive dysfunction.
• Forty-five of the 55 patients were diagnosed with corporal veno-occlusive dysfunction. 3D-CT cavernosography revealed drainage veins in all 45 cases, including cavernous veins, dorsal veins, crural veins and other emissary veins. • Compared with 3D-CT cavernosography, observing cavernous veins and the proximal part of the deep dorsal veins using MIP imaging was especially difficult because the origins of the penile veins are often behind the pelvic bone or cavernous body. • Of the patients who seemingly had leakage via the deep dorsal vein, 80.6% did not in fact have leakage via this vein, but had other leakages. The image resolution of 3D-CT cavernosography was significantly higher than that of MIP.
• 3D-CT cavernosography can provide high-resolution images of venous drainage from any angle. We conclude that the images obtained by 3D-CT cavernosography are very helpful for both the diagnosis of corporal veno-occlusive dysfunction and the anatomical study of the human penile venous system.
探讨三维(3D)CT 海绵体静脉造影在诊断海绵体静脉闭塞性功能障碍中的可行性。
共纳入 55 例对磷酸二酯酶 5 抑制剂反应不佳的患者。我们使用 60mg 盐酸罂粟碱进行药效学海绵体灌注和海绵体造影。在 90mmHg 海绵体腔内压下进行海绵体造影,使用多层 CT 扫描系统。使用 aquarius net station,ver.2 计算机软件重建 3D 图像。与传统海绵体造影相比,使用最大强度投影(MIP)图像。如果能够以 20ml/min 的流速或维持 90mmHg 的海绵体腔内压,则表明存在静脉闭塞性功能障碍。
55 例患者中,45 例诊断为海绵体静脉闭塞性功能障碍。3D-CT 海绵体造影显示所有 45 例均存在引流静脉,包括海绵体静脉、背侧静脉、小腿静脉和其他交通静脉。与 3D-CT 海绵体造影相比,通过 MIP 成像观察海绵体静脉和深部背侧静脉的近端部分尤其困难,因为阴茎静脉的起源通常位于骨盆或海绵体的后面。在那些似乎通过深部背侧静脉漏的患者中,80.6%的患者实际上并没有通过该静脉漏,而是存在其他漏。3D-CT 海绵体造影的图像分辨率明显高于 MIP。
3D-CT 海绵体静脉造影可以从任何角度提供静脉引流的高分辨率图像。我们得出结论,3D-CT 海绵体静脉造影获得的图像对诊断海绵体静脉闭塞性功能障碍和人类阴茎静脉系统的解剖学研究非常有帮助。