Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.
Addict Behav. 2011 Jan-Feb;36(1-2):144-7. doi: 10.1016/j.addbeh.2010.08.024. Epub 2010 Sep 24.
To examine changes in nicotine withdrawal, nicotine craving, self-efficacy to quit smoking, and perceived control over withdrawal symptoms as predictors of smoking cessation following behavioral counseling and nicotine replacement therapy in a sample of smokers.
The data were ascertained from a randomized effectiveness trial comparing nicotine patch to nicotine lozenge. Predictors of smoking cessation were assessed at baseline and 5 weeks post-baseline, and 24-hour point prevalence abstinence, biochemically confirmed, was assessed at the end-of-treatment (week 15) and 6 months after a target quit date (week 27).
642 treatment-seeking smokers randomized to 12 weeks of nicotine patch or nicotine lozenge.
Participants who showed a greater increase in self-efficacy to quit smoking (OR=1.09, 95% CI: 1.02-1.16, p=.01) and perceived control over withdrawal symptoms (OR=1.02, 95% CI: 1.00-1.04, p=.05) were significantly more likely to have quit smoking at week 15. Participants who showed a greater increase in self-efficacy to quit smoking (OR=1.04, 95% CI: 1.01-1.06, p=.01) were significantly more likely to have quit smoking at week 27. Changes in withdrawal symptoms and craving were not related to week 15 or week 27 abstinence rates.
The results highlight two relatively under-studied potential psychological predictors of abstinence following treatment for nicotine dependence. Behavioral counseling interventions to promote smoking cessation should help smokers develop confidence in their ability to quit smoking and increase their sense of control over withdrawal symptoms to increase their chances for cessation.
在吸烟者的行为咨询和尼古丁替代治疗中,检查尼古丁戒断、尼古丁渴求、戒烟自我效能和对戒断症状的控制感的变化,作为戒烟的预测指标。
数据来自比较尼古丁贴片和尼古丁含片的随机有效性试验。在基线和基线后 5 周评估戒烟预测指标,在治疗结束时(第 15 周)和目标戒烟日期(第 27 周)后 6 个月通过 24 小时点患病率(生物化学确认)评估戒烟情况。
642 名寻求治疗的吸烟者,随机分为 12 周尼古丁贴片或尼古丁含片。
戒烟自我效能感(OR=1.09,95% CI:1.02-1.16,p=.01)和对戒断症状控制感(OR=1.02,95% CI:1.00-1.04,p=.05)显著增加的参与者在第 15 周更有可能戒烟。戒烟自我效能感(OR=1.04,95% CI:1.01-1.06,p=.01)显著增加的参与者在第 27 周更有可能戒烟。戒断症状和渴求的变化与第 15 周或第 27 周的戒烟率无关。
结果突出了两个相对研究较少的戒烟后可能的心理预测指标。促进戒烟的行为咨询干预措施应该帮助吸烟者增强戒烟能力的信心,增加对戒断症状的控制感,以增加戒烟的机会。