School of Psychology, University of Southampton, UK.
Int J Psychophysiol. 2011 Feb;79(2):97-105. doi: 10.1016/j.ijpsycho.2010.09.007. Epub 2010 Sep 24.
Age-related effects on novelty processing have been reported and are linked with changes in frontal lobe functioning. Auditory novelty processing and habituation of the novelty P3 event-related potential were investigated in younger and older adults. Novelty processing, as indexed by novelty P3 amplitude, was similar between the groups. We found the expected decrease in novelty P3 amplitude at frontal regions in younger adults with repetition of novel stimuli. In contrast, older adults displayed no evidence of habituation, rather an increase in novelty P3 amplitude at frontal sites was found when novel stimuli were repeated. We extend current understanding of novelty processing in normal aging by comparing this habituation related-hyperfrontality with intellectual functioning.
年龄相关的新颖性处理效应已经被报道，并与额叶功能的变化有关。本研究旨在调查年轻和年长成人的听觉新颖性处理和新颖 P3 事件相关电位的习惯化。新颖 P3 振幅作为新颖性处理的指标，在两组之间相似。我们发现，随着新颖刺激的重复，年轻成年人在前额区域的新颖 P3 振幅预期下降。相比之下，年长成年人没有表现出习惯化的迹象，而是在前额部位发现了新颖 P3 振幅的增加，当重复呈现新颖刺激时。我们通过将这种与习惯化相关的超额叶现象与智力功能进行比较，扩展了对正常衰老中新颖性处理的理解。
