Department of Pediatrics (Pediatric Hematology), Emma Children's Hospital/Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
Thromb Res. 2010 Dec;126(6):465-70. doi: 10.1016/j.thromres.2010.08.027. Epub 2010 Sep 27.
Survival of children with chronic intestinal failure has increased as result of administration of home parenteral nutrition. Crucial for the successful management of home parenteral nutrition is the availability of an adequate central venous access. Venous access can be fraught by episodes of catheter-infection, recurrent replacements of catheters and finally catheter-related thrombosis. Management and prevention of catheter-related thrombosis are of vital importance. For patients with compromised venous access, alternative measures are reported, most of them used as a bridge to bowel transplantation.
儿童慢性肠衰竭的存活率因家庭肠外营养的应用而提高。成功管理家庭肠外营养的关键是获得足够的中心静脉通路。静脉通路可能会出现导管感染、导管反复更换，最终导致导管相关血栓形成。因此，管理和预防导管相关血栓形成至关重要。对于静脉通路受损的患者，有报道称可以采取替代措施，其中大多数措施被用作肠移植的桥梁。
