Williams N, Scott N A, Irving M H
Department of Surgery, University of Manchester, Hope Hospital, Salford.
Ann R Coll Surg Engl. 1994 Nov;76(6):384-6.
Until recently, Home Parenteral Nutrition (HPN) has been the only real option for patients with intestinal failure. Small bowel transplantation (SBT) is advancing rapidly, however, and may soon provide an alternative for these patients. One of the arguments in favour of SBT is the alleged morbidity of prolonged parenteral nutrition. We have assessed the catheter-related morbidity in a large cohort of patients on HPN. A total of 88 central venous catheters were required in 50 patients. The main complications were sepsis (24 episodes) and occlusion (18 episodes). The overall incidence of catheter-related morbidity was one episode per 46 patient-months of HPN.
直到最近,家庭肠外营养(HPN)一直是肠衰竭患者唯一真正的选择。然而,小肠移植(SBT)正在迅速发展,可能很快就能为这些患者提供另一种选择。支持小肠移植的论据之一是长期肠外营养存在所谓的发病率问题。我们评估了一大群接受家庭肠外营养患者的导管相关发病率。50名患者共需要88根中心静脉导管。主要并发症为败血症(24例)和堵塞(18例)。导管相关发病率的总体发生率为每46个家庭肠外营养患者月发生1例。