Lilienfeld D E, Sekkor D, Simpson S, Perl D P, Ehland J, Marsh G, Chan E, Godbold J H, Landrigan P J
Division of Environmental and Occupational Medicine, Mount Sinai School of Medicine, New York, N.Y.
Neuroepidemiology. 1990;9(5):243-7. doi: 10.1159/000110780.
To evaluate temporal changes in the geographic distribution of Parkinson's disease (PD) mortality in the United States, we reviewed death rates for PD in the nine regions of the United States for 1980-1984. Age-adjusted mortality for all ages and for the elderly (65 years of age and older) was analyzed. Variation in PD mortality was observed among the regions for all demographic groups. The patterns were different from those reported during 1959-1961. Changing geographic patterns in mortality provide evidence for an environmental etiology for PD.
为评估美国帕金森病（PD）死亡率地理分布的时间变化，我们回顾了1980 - 1984年美国九个地区的PD死亡率。分析了所有年龄段以及老年人（65岁及以上）的年龄调整死亡率。在所有人口群体的各地区中均观察到PD死亡率存在差异。这些模式与1959 - 1961年期间报告的模式不同。死亡率地理模式的变化为PD的环境病因提供了证据。
