Vanacore N, Bonifati V, Bellatreccia A, Edito F, Meco G
Department of Neurological Science, University La Sapienza, Rome, Italy.
Neuroepidemiology. 1992;11(2):65-73. doi: 10.1159/000110914.
The mortality rates (MRs) for Parkinson's disease (PD) and parkinsonism were analyzed for the period 1969-1987 in Italy, considering the population aged greater than or equal to 25. MRs were then age-adjusted taking the 1981 Italian population as standard. We found an increase in MRs for PD during the period studied. The Italian average annual age-adjusted MR was 5.73, ranging from 4.76 (1969) to 6.81 (1985). Moreover we noticed some interesting differences in the geographic distribution of MRs between the five big areas Italy was divided into. We also found that, while the MR for the ages 65-79 years was quite constant in the period studied, there was a marked increase in the MR for ages greater than 79 years from 1980 onwards. The geographic differences we found in MRs deserve to be analyzed in further epidemiological studies.
对1969年至1987年期间意大利25岁及以上人群帕金森病（PD）和帕金森综合征的死亡率（MRs）进行了分析。然后以1981年意大利人口为标准对MRs进行年龄调整。我们发现在研究期间PD的MRs有所增加。意大利年龄调整后的年平均MR为5.73，范围从4.76（1969年）到6.81（1985年）。此外，我们注意到意大利划分的五个大区之间MRs的地理分布存在一些有趣的差异。我们还发现，虽然65至79岁年龄组的MR在研究期间相当稳定，但自1980年起，79岁以上年龄组的MR显著增加。我们发现的MRs的地理差异值得在进一步的流行病学研究中进行分析。
