Department of Kinesiology, Applied Neuromechanics Research Laboratory, University of North Carolina at Greensboro, 1408 Walker Ave, Greensboro, North Carolina 27402, USA.
J Orthop Res. 2010 Nov;28(11):1411-7. doi: 10.1002/jor.21145.
Changes in anterior knee laxity (AKL), genu recurvatum (GR) and general joint laxity (GJL) were quantified across days of the early follicular and early luteal phases of the menstrual cycle in 66 females, and the similarity in their pattern of cyclic variations examined. Laxity was measured on each of the first 6 days of menses (M1-M6) and the first 8 days following ovulation (L1-L8) over two cycles. The largest mean differences were observed between L5 and L8 for AKL (0.32 mm), and between L5 and M1 for GR (0.56°) and GJL (0.26) (p < 0.013). At the individual level, mean absolute cyclic changes in AKL (1.8 ± 0.7 mm, 1.6 ± 0.7 mm), GR (2.8 ± 1.0°, 2.4 ± 1.0°), and GJL (1.1 ± 1.1, 0.7 ± 1.0) were more apparent, with minimum, maximum and delta values being quite consistent from month to month (ICC(2,3) = 0.51-0.98). Although the average daily pattern of change in laxity was quite similar between variables (Spearman correlation range 0.61 and 0.90), correlations between laxity measures at the individual level were much lower (range -0.07 to 0.43). Substantial, similar, and reproducible cyclic changes in AKL, GR, and GJL were observed across the menstrual cycle, with the magnitude and pattern of cyclic changes varying considerably among females.
在两个周期中，66 名女性的月经周期早期卵泡期和早期黄体期的前膝松弛度（AKL）、膝反屈（GR）和一般关节松弛度（GJL）发生变化，并检查其周期性变化模式的相似性。在月经的前 6 天（M1-M6）和排卵后的前 8 天（L1-L8）的每一天测量松弛度。AKL 的最大平均差异观察到在 L5 和 L8 之间（0.32 毫米），GR（0.56°）和 GJL（0.26）的最大平均差异观察到在 L5 和 M1 之间（p < 0.013）。在个体水平上，AKL（1.8±0.7 毫米，1.6±0.7 毫米）、GR（2.8±1.0°，2.4±1.0°）和 GJL（1.1±1.1，0.7±1.0）的平均绝对循环变化更为明显，最小值、最大值和增量值在每个月都相当一致（ICC(2,3)=0.51-0.98）。尽管松弛度变化的平均日常模式在变量之间非常相似（Spearman 相关系数范围为 0.61 到 0.90），但个体水平上的松弛度测量值之间的相关性要低得多（范围为-0.07 到 0.43）。在月经周期中观察到 AKL、GR 和 GJL 明显、相似且可重复的周期性变化，女性之间的循环变化幅度和模式差异很大。
