Lieb W E, Shields J A, Cohen S M, Merton D A, Mitchell D G, Shields C L, Goldberg B B
Oncology Service, Wills Eye Hospital, Philadelphia, PA 19107.
Ophthalmology. 1990 Dec;97(12):1660-4. doi: 10.1016/s0161-6420(90)32364-3.
Forty-four intraocular mass lesions were studied using a new, non-invasive ultrasound technique known as color Doppler imaging (CDI). This technique displays color-encoded Doppler flow information throughout a two-dimensional gray scale image thus providing selective analysis of Doppler spectra in small vessels using pulsed Doppler. Abnormal Doppler shifts were demonstrated within 39 neoplastic lesions studied, but Doppler shifts could not be detected in three tumor-simulating lesions. In a group of 12 choroidal melanomas studied after radiation therapy, lower Doppler shifts were seen compared with a group of 28 tumors before therapy. This change in Doppler shift may reflect the decreased vascular supply of the tumor. Color Doppler imaging may be of value as an additional useful tool in the diagnosis and management of intraocular tumors.
采用一种名为彩色多普勒成像（CDI）的新型非侵入性超声技术，对44例眼内肿块病变进行了研究。该技术在二维灰度图像中显示彩色编码的多普勒血流信息，从而使用脉冲多普勒对小血管中的多普勒频谱进行选择性分析。在所研究的39例肿瘤性病变中均显示出异常的多普勒频移，但在3例肿瘤样病变中未检测到多普勒频移。在一组接受放射治疗后的12例脉络膜黑色素瘤中，与28例治疗前的肿瘤相比，观察到较低的多普勒频移。这种多普勒频移的变化可能反映了肿瘤血管供应的减少。彩色多普勒成像作为眼内肿瘤诊断和管理中的一种额外有用工具可能具有价值。
