Svĕrák J, Hejcmanová D, Peregrin J, Erben J
Clinic of Ophthalmology, Charles University's, Faculty of Medicine, Hradec Králové.
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove. 1990;33(3):319-23.
In the last 11 years, the neuroretinopathy is reported to occur in 26 dialyzed patients, what represents 5.3% of all patients treated. During the last 4 years, the occurrence rate showed the decrease to 1.6%. The mentioned disease occurs most frequently by the first two years of treatment with dialysis. The averaged survival rate after the onset of neuroretinopathy is ranged as 19.4 mos. in 16 died patients. The disease occurred in 13 patients under the condition of normal diastolic pressure. Metabolic disorder characterized with high levels of serum nitrogenic substances may be further factor inducing the onset of neuroretinopathy backgrounded by cerebral oedema. Since neuroretinopathy consequentially worsens both the subjective (visual acuity, sensitivity to the contrast) and objective (electric activity) sight functions, the appropriate attempt is to be made in achieving rapidly retrogression of pathologic retinal changes by modification of dialysis process.
在过去11年中，据报道有26例透析患者发生了神经视网膜病变，占所有接受治疗患者的5.3%。在过去4年中，发生率降至1.6%。上述疾病在透析治疗的头两年最常发生。16例死亡患者发生神经视网膜病变后的平均生存率为19.4个月。该疾病在13例舒张压正常的患者中发生。以血清含氮物质水平升高为特征的代谢紊乱可能是在脑水肿背景下诱发神经视网膜病变的进一步因素。由于神经视网膜病变会导致主观（视力、对比度敏感度）和客观（电活动）视觉功能恶化，因此应通过调整透析过程来迅速促使病理性视网膜变化消退。
