Polymorphous light eruption: PUVA-induced skin hyporeactivity.

Eight patients with polymorphous light eruption (PLE) were treated with the 8-methoxypsoralen (0.6 mg/kg) and UV-A given in an ordinary PUVA cabin. Excellent or good results were observed in 4 and moderate in others remained patients. It is concluded that PUVA treatment is a safe form of therapy which exercises its beneficial effect in the patients with PLE. Various theories concerning the mode of action of photochemotherapy in PLE are discussed in this paper.