Department of Neurological Surgery, Stony Brook University, Stony Brook, NY 11794-8122, USA.
Stroke. 2010 Oct;41(10 Suppl):S21-5. doi: 10.1161/STROKEAHA.110.595066.
The latest class of neuroendovascular devices being evaluated is intended to treat cerebral aneurysms. In addition to inducing flow stasis-mediated thrombosis of aneurysms and thus at times being referred to as flow diverters, these devices reconstitute pathologic arterial segments to near-physiologic normalcy. The successful implementation of such an endoluminal scaffold for vascular reconstruction in the cerebral circulation requires careful consideration of various factors drawn from engineering, physics, and biological sciences. Here we review some of these factors.
目前正在评估的最新一代神经血管设备旨在治疗脑动脉瘤。除了诱导动脉瘤的血流停滞介导的血栓形成,因此有时被称为血流分流器之外,这些设备还使病理性动脉节段重建接近生理正常。在脑循环中成功实施这种血管内支架的血管重建需要仔细考虑来自工程、物理和生物科学的各种因素。在这里,我们回顾了其中的一些因素。