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本文引用的文献

1
Adjuvant therapy for completely resected stage II colon cancer.完全切除的II期结肠癌的辅助治疗。
Cochrane Database Syst Rev. 2008 Jul 16;2008(3):CD005390. doi: 10.1002/14651858.CD005390.pub2.
2
Biomarker discovery for colon cancer using a 761 gene RT-PCR assay.使用761基因RT-PCR检测法发现结肠癌生物标志物。
BMC Genomics. 2007 Aug 15;8:279. doi: 10.1186/1471-2164-8-279.

Oncotype DX肿瘤基因表达谱在II期结肠癌中的应用：预后评估、风险预测

Oncotype DX tumor gene expression profiling in stage II colon cancer. Application: prognostic, risk prediction.

作者信息

Webber Elizabeth M, Lin Jennifer S

机构信息

Kaiser Permanente Center for Health Research.

出版信息

PLoS Curr. 2010 Sep 2;2:RRN1177. doi: 10.1371/currents.RRN1177.

DOI:10.1371/currents.RRN1177
PMID:20877447
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2940137/
Abstract

Overall five-year survival for patients with stage-II colon cancer averages 75% after surgery alone. However, some of these patients have poorer outcomes, similar to patients with stage-III disease. The proposed use of the Oncotype DX assay is to improve risk stratification for recurrence in stage-II colon cancer.

摘要

II期结肠癌患者仅接受手术后的总体五年生存率平均为75%。然而，其中一些患者的预后较差，与III期疾病患者相似。拟使用的Oncotype DX检测旨在改善II期结肠癌复发的风险分层。