Department of Bio and Brain Engineering, College of Life Science and Bioengineering, Korea Advanced Institute of Science and Technology (KAIST), 335 Gwahangno, Yuseong-gu, Daejeon 305-701, Republic of Korea.
Biomicrofluidics. 2010 Aug 31;4(3):034110. doi: 10.1063/1.3486609.
We present a microfluidic parallel circuit that directly compares the test channel of an unknown hydraulic resistance with the reference channel with a known resistance, thereby measuring the unknown resistance without any measurement setup, such as standard pressure gauges. Many of microfluidic applications require the precise transport of fluid along a channel network with complex patterns. Therefore, it is important to accurately characterize and measure the hydraulic resistance of each channel segment, and determines whether the device principle works well. However, there is no fluidic device that includes features, such as the ability to diagnose microfluidic problems by measuring the hydraulic resistance of a microfluidic component in microscales. To address the above need, we demonstrate a simple strategy to measure an unknown hydraulic resistance, by characterizing the hydraulic resistance of microchannels with different widths and defining an equivalent linear channel of a microchannel with repeated patterns of a sudden contraction and expansion.
我们提出了一种微流控并联电路，该电路直接将未知水力阻力的测试通道与具有已知阻力的参考通道进行比较，从而在无需任何测量设置（例如标准压力表）的情况下测量未知阻力。许多微流控应用需要沿着具有复杂图案的通道网络精确地输送流体。因此，准确地描述和测量每个通道段的水力阻力并确定器件原理是否运行良好非常重要。但是，没有能够通过测量微尺度下微流控元件的水力阻力来诊断微流控问题的流体装置。为了解决上述需求，我们通过对具有不同宽度的微通道的水力阻力进行特征化，并定义了具有重复突然收缩和扩张图案的微通道的等效线性通道，展示了一种测量未知水力阻力的简单策略。
