在聚乙二醇溶液中分子拥挤作用催化的 DNA 链交换。

DNA strand exchange catalyzed by molecular crowding in PEG solutions.

机构信息

Department of Chemical and Biological Engineering, Chalmers University of Technology, S-41296, Gothenburg, Sweden.

出版信息

Chem Commun (Camb). 2010 Nov 21;46(43):8231-3. doi: 10.1039/c0cc03117h. Epub 2010 Sep 29.

PMID:20877908

Abstract

DNA strand exchange is catalyzed by molecular crowding and hydrophobic interactions in concentrated aqueous solutions of polyethylene glycol, a discovery of relevance for understanding the function of recombination enzymes and with potential applications to DNA nanotechnology.

摘要

DNA 链交换在聚乙二醇的浓水溶液中受到分子拥挤和疏水相互作用的催化，这一发现与理解重组酶的功能有关，并具有潜在的 DNA 纳米技术应用。