乙醇和乙醛对肝脏溶酶体组织蛋白酶A活性及释放的影响。
Influence of ethanol and acetaldehyde on the activity and release of cathepsin A from liver lysosomes.
作者信息
Ostrowska H, Kamiński J
机构信息
Department of Instrumental Analysis, Medical Academy, Białystok, Poland.
出版信息
Acta Biochim Pol. 1990;37(1):141-4.
PMID:2087903
Abstract
Ethanol and acetaldehyde inhibited the activity of cathepsin A. In vitro ethanol did not release cathepsin A from liver lysosomes whereas acetaldehyde of high concentration did. Intoxication of rats with ethanol and acetaldehyde evoked a transient increase of free and bound cathepsin A.
摘要
乙醇和乙醛抑制组织蛋白酶A的活性。在体外，乙醇不会从肝溶酶体中释放组织蛋白酶A，而高浓度的乙醛则会。用乙醇和乙醛使大鼠中毒会引起游离和结合的组织蛋白酶A短暂增加。
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