Skrzydlewski Z, Worowski K, Skrzydlewska E
Acta Biochim Pol. 1985;32(3):271-7.
Intoxication with ethanol and acetaldehyde resulted in a marked increase of the acid proteolytic activity in the post-lysosomal supernatant of rat kidney, lung, and liver, while the content of protein and acid-soluble tyrosine remained practically unchanged. Proteins of the post-lysosomal supernatant were degraded in vitro by the endogenous proteinase(s) of lysosomal origin at pH 3.5 and 5.5 but not at pH 7.0.
乙醇和乙醛中毒导致大鼠肾脏、肺和肝脏溶酶体后上清液中的酸性蛋白水解活性显著增加，而蛋白质和酸溶性酪氨酸的含量实际上保持不变。溶酶体后上清液中的蛋白质在体外于pH 3.5和5.5时被溶酶体来源的内源性蛋白酶降解，但在pH 7.0时不被降解。
