[实验性急性脑内血肿的磁共振成像（MRI）影像学特征]

[MRI semiotics features of experimental acute intracerebral hematomas].

作者信息

Burenchev D V, Skvortsova V I, Tvorogova T V, Guseva O I, Gubskiĭ L V, Kupriianov D A, Pirogov Iu A

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2009;109(12 Suppl 2):41-6.

PMID:20879104

Abstract

The aim of this study was to assess the possibility of revealing intracerebral hematomas (ICH), using MRI, within the first hours after onset and to determine their MRI semiotics features. Thirty animals with experimental ICH were studied. A method of two-stage introduction of autologous blood was used to develop ICH as human spontaneous intracranial hematomas. Within 3-5h after blood introduction to the rat brain. The control MRI was performed in the 3rd and 7th days after blood injections. ICH were definitely identified in the first MRI scans. The MRI semiotics features of acute ICH and their transformations were assessed. The high sensitivity of MRI to ICH as well as the uniform manifestations in all animals were shown. In conclusion, the method has high specificity for acute ICH detection.

摘要

本研究的目的是评估在发病后的最初几小时内使用磁共振成像（MRI）检测脑内血肿（ICH）的可能性，并确定其MRI影像学特征。对30只患有实验性ICH的动物进行了研究。采用自体血两阶段注入法来形成ICH，如同人类自发性颅内血肿一样。在将血液注入大鼠脑内后的3 - 5小时内。在注射血液后的第3天和第7天进行对照MRI检查。在首次MRI扫描中就明确识别出了ICH。评估了急性ICH的MRI影像学特征及其变化。结果显示MRI对ICH具有高敏感性，并且在所有动物中表现一致。总之，该方法对急性ICH检测具有高特异性。