Nakamura T, Kadoya S, Umemori T, Suzuki T, Kwaku R
Department of Neurosurgery, Kanazawa Medical University, Ishikawa, Japan.
No Shinkei Geka. 1988 Apr;16(4):435-9.
A case of multiple spontaneous intracerebral hematomas is presented. A 67-year-old man with 7 years history of hypertension had sudden clumsiness in his right hand and an hour later dysarthria appeared. A CT scan taken 3 hours after the onset revealed two well demarcated high density areas in the left putamen and in the parietal subcortex. A diagnosis of multiple intracerebral hematomas was made. On neurological examination he was midly stuporous (13 points of Glasgow Coma Scale). Dysarthria, right hemiparesis and right extensor plantar response were seen. CT scan of 6 hours later disclosed the same findings as the previous study. He recovered well and neurologically free in a few days. On the following CT scans both hematomas were isodense 2 weeks later, and ring-like enhancement effect was noted. CT scan showed normal appearance 7 weeks later. On MRI using 0.5 T unit t-1 and t-2 weighted spin echo images of these hematomas also showed the similar chronological changes. The history, these CT and MRI studies suggest that two hematomas of this case occurred almost simultaneously in one cerebral hemisphere. No causative factors such as blood dyscrasias, AVM, angioma, septicemia, malignancies or sinus thrombosis was identified. We consider that a hypertensive intracerebral hematoma of the putamen was followed by the parietal intracerebral hematoma within a few hours, although amyloid angiopathy was not completely excluded because no cerebral biopsy of the lesion was performed.
本文报告一例多发性自发性脑内血肿病例。一名67岁男性,有7年高血压病史,右手突然出现笨拙,1小时后出现构音障碍。发病3小时后进行的CT扫描显示左侧壳核和顶叶皮质下有两个边界清晰的高密度区。诊断为多发性脑内血肿。神经系统检查时,他处于轻度昏迷状态(格拉斯哥昏迷量表评分为13分)。可见构音障碍、右侧偏瘫和右侧伸跖反射。6小时后的CT扫描结果与之前的检查相同。他在几天内恢复良好,神经系统症状消失。在接下来的CT扫描中,两周后两个血肿均呈等密度,并可见环状强化效应。7周后CT扫描显示外观正常。使用0.5T设备进行的MRI检查中,这些血肿的t-1和t-2加权自旋回波图像也显示出类似的时间变化。病史、这些CT和MRI研究表明,该病例的两个血肿几乎同时发生在一个脑半球。未发现血液系统疾病、动静脉畸形、血管瘤、败血症、恶性肿瘤或窦血栓形成等致病因素。我们认为,壳核的高血压性脑内血肿在数小时内继发顶叶脑内血肿,尽管由于未进行病变的脑活检,淀粉样血管病不能完全排除。