Center for Health Care Evaluation, VA Palo Alto Health Care System and Stanford University School of Medicine . Menlo Park, CA 94025, USA.
Popul Health Manag. 2010 Oct;13(5):263-8. doi: 10.1089/pop.2009.0060.
We sought to determine the sex- and age-specific risk of mortality associated with scores on the 3-item Alcohol Use Disorder Identification Test-Consumption (AUDIT-C) questionnaire using data from a national sample of Veterans Health Administration (VHA) patients. Men (N = 215,924) and women (N = 9168) who completed the AUDIT-C in a patient survey were followed for 24 months. AUDIT-C categories (0, 1-4, 5-8, 9-12) were evaluated as predictors of mortality in logistic regression models, adjusted for age, race, education, marital status, smoking, depression, and comorbidities. For women, AUDIT-C scores of 9-12 were associated with a significantly increased risk of death compared to the AUDIT-C 1-4 group (odds ratio [OR] 7.09; 95% confidence interval [CI] = 2.67, 18.82). For men overall, AUDIT-C scores of 5-8 and 9-12 were associated with increased risk of death compared to the AUDIT-C 1-4 group (OR 1.13, 95% CI = 1.05, 1.21, and OR 1.63, 95% CI = 1.45, 1.84, respectively) but these associations varied by age. These results provide sex- and age-tailored risk information that clinicians can use in evidence-based conversations with patients about the health-related risks of their alcohol consumption. This study adds to the growing literature establishing the AUDIT-C as a scaled marker of alcohol-related risk or "vital sign" that might facilitate the detection and management of alcohol-related risks and problems.
我们旨在通过退伍军人健康管理局 (VHA) 患者的全国样本数据，确定三项目酒精使用障碍识别测试 - 摄入量 (AUDIT-C) 问卷评分与死亡率相关的性别和年龄特定风险。在患者调查中完成 AUDIT-C 的男性 (N=215924) 和女性 (N=9168) 随访了 24 个月。在逻辑回归模型中，将 AUDIT-C 类别 (0、1-4、5-8、9-12) 评估为死亡率的预测因子，调整了年龄、种族、教育程度、婚姻状况、吸烟、抑郁和合并症。对于女性，与 AUDIT-C 1-4 组相比，AUDIT-C 评分 9-12 与死亡风险显著增加相关 (比值比 [OR] 7.09；95%置信区间 [CI] = 2.67, 18.82)。对于总体男性，与 AUDIT-C 1-4 组相比，AUDIT-C 评分 5-8 和 9-12 与死亡风险增加相关 (OR 1.13, 95% CI = 1.05, 1.21，和 OR 1.63, 95% CI = 1.45, 1.84)，但这些关联因年龄而异。这些结果提供了性别和年龄定制的风险信息，临床医生可以在与患者进行基于证据的对话中使用这些信息，讨论他们饮酒的健康相关风险。本研究增加了越来越多的文献，这些文献确立了 AUDIT-C 作为酒精相关风险的量表标记物或“生命体征”，可以促进酒精相关风险和问题的检测和管理。
