Department of Diagnostic Imaging, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Cancer Imaging. 2010 Oct 4;10 Spec no A(1A):S92-8. doi: 10.1102/1470-7330.2010.9033.
Perineural tumour spread refers to a contiguous neoplastic extension along a nerve. As it may be clinically silent, imaging plays a pivotal role in the evaluation and delineation of perineural infiltration in head and neck malignancies, which in turn affects treatment planning. This article focuses on the imaging features of perineural spread of head and neck tumours. The important potential perineural pathways and the possible underlying pathogenesis of this phenomenon are also reviewed.
神经周围肿瘤扩散是指沿着神经的连续肿瘤延伸。由于其可能在临床上无明显症状，因此影像学在评估和描绘头颈部恶性肿瘤的神经周围浸润中起着关键作用，进而影响治疗计划。本文重点介绍头颈部肿瘤神经周围扩散的影像学特征。还回顾了这种现象的重要潜在神经通路和可能的潜在发病机制。
