Nayak B Shivananda, Marshall Julien R, Isitor Godwin
Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad.
Indian J Exp Biol. 2010 Jun;48(6):572-6.
The extract of K. pinnata was evaluated for its wound healing activity by using excision wound model in rats. On day 11, animals treated with the ethanolic leaf extract exhibited 86.33% reduction in the wound area, compared to petroleum jelly treated control (69.36%) and the mupirocin treated standard (85.49%). The hydroxyproline content of extract treated animals was higher, as compared to control and the standard groups. Histological analysis was also consistent with the proposal that K. pinnata leaf extract exhibits significant wound healing potential. The increased rate of wound contraction and hydroxyproline content in the extract treated animals supports the claims made by traditional healers of the benefits obtained from the medicinal use of K. pinnata.
通过在大鼠身上使用切除伤口模型，对匙羹藤提取物的伤口愈合活性进行了评估。在第11天，与用凡士林处理的对照组（69.36%）和用莫匹罗星处理的标准组（85.49%）相比，用乙醇叶提取物处理的动物伤口面积减少了86.33%。与对照组和标准组相比，提取物处理动物的羟脯氨酸含量更高。组织学分析也与匙羹藤叶提取物具有显著伤口愈合潜力的观点一致。提取物处理动物伤口收缩率和羟脯氨酸含量的增加，支持了传统治疗师关于从匙羹藤药用中获得益处的说法。
Zotero 插件