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A third allele of the HPA-5 (Br) platelet alloantigen system identified in investigating a case of neonatal thrombocytopenia.

作者信息

Peterson Julie A, Gitter Maria L, Pietz Bradley, Bellissimo Daniel, Curtis Brian, Aster Richard

出版信息

Transfusion. 2010 Aug;50(8):1855-6. doi: 10.1111/j.1537-2995.2010.02660.x.

DOI:10.1111/j.1537-2995.2010.02660.x
PMID:20883258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3576880/
Abstract
摘要

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A third allele of the HPA-5 (Br) platelet alloantigen system identified in investigating a case of neonatal thrombocytopenia.在调查一例新生儿血小板减少症病例时发现了血小板同种抗原系统HPA - 5(Br)的第三个等位基因。
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引用本文的文献

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High-Throughput Screening of Blood Donors for Twelve Human Platelet Antigen Systems Using Next-Generation Sequencing Reveals Detection of Rare Polymorphisms and Two Novel Protein-Changing Variants.使用下一代测序技术对献血者进行12种人类血小板抗原系统的高通量筛选,发现了罕见多态性和两个新型蛋白质改变变体。
Transfus Med Hemother. 2020 Feb;47(1):33-44. doi: 10.1159/000504894. Epub 2020 Jan 8.

本文引用的文献

1
Genotyping for human platelet alloantigen polymorphisms: applications in the diagnosis of alloimmune platelet disorders.人类血小板同种抗原多态性的基因分型:在同种免疫性血小板疾病诊断中的应用
Semin Thromb Hemost. 2008 Sep;34(6):539-48. doi: 10.1055/s-0028-1103365. Epub 2008 Nov 28.
2
The human platelet alloantigens Br(a) and Brb are associated with a single amino acid polymorphism on glycoprotein Ia (integrin subunit alpha 2).人类血小板同种异体抗原Br(a)和Br(b)与糖蛋白Ia(整合素α2亚基)上的单个氨基酸多态性相关。
J Clin Invest. 1993 Nov;92(5):2427-32. doi: 10.1172/JCI116849.
3
The Bra/Brb alloantigen system on human platelets.人类血小板上的Bra/Brb同种异体抗原系统。
Blood. 1989 Jun;73(8):2219-23.
4
HPA-5b (Br(a)) neonatal alloimmune thrombocytopenia: clinical and immunological analysis of 39 cases.HPA-5b(Br(a))新生儿同种免疫性血小板减少症:39例临床与免疫学分析
Br J Haematol. 1991 Jul;78(3):425-9. doi: 10.1111/j.1365-2141.1991.tb04459.x.
5
[Neonatal thrombocyte values in children with Down's syndrome and other autosome trisomies].[唐氏综合征及其他常染色体三体患儿的新生儿血小板值]
Helv Paediatr Acta. 1979;34(6):545-55.