Department of Public Health, Hjelt Institute, University of Helsinki, Finland.
Addiction. 2011 Jan;106(1):170-7. doi: 10.1111/j.1360-0443.2010.03112.x. Epub 2010 Sep 30.
To examine the association between diurnal type and smoking status and nicotine dependence (ND).
A cohort study using random-effects model regressions for repeated longitudinal panel data was used to analyse smoking status by diurnal type. Regression analyses examined the association between diurnal type and ND.
A total of 23, 289 same-sex adult twin individuals from Finnish Twin Cohort. Nicotine dependence was studied in a subsample of 676 twin individuals.
Subjects were classified by self-report into four categories: morning type, somewhat morning type, somewhat evening type, evening type (in 1981). Smoking status was defined as current and ever smoking (in 1975, 1981 and 1990). ND was measured by DSM-IV and Fagerström Test for Nicotine Dependence (FTND) (during 2001-05). Findings Evening types of both genders were much more likely to be current (OR = 2.91, 95% CI 2.50, 3.38) and life-time smokers (OR = 2.67, 95% CI 2.96, 4.07) compared to morning types. Evening types were less likely to stop smoking. The risk of nicotine dependence assessed by DSM-IV criteria was higher among evening types (OR = 2.78, 95% CI 1.64, 4.72). Evening types scored 0.59 (95% CI 0.01, 1.17) points higher than morning types on the FTND. Adjustment for potential confounders did not change these associations.
Being an evening type is associated independently with a higher risk of being a current smoker, being more highly dependent upon cigarettes and a lower likelihood of stopping smoking. Understanding the cause of these associations could elucidate the causes of tobacco addiction.
探讨昼夜类型与吸烟状况和尼古丁依赖(ND)之间的关系。
使用重复纵向面板数据的随机效应模型回归分析,根据昼夜类型分析吸烟状况。回归分析探讨了昼夜类型与 ND 之间的关系。
来自芬兰双胞胎队列的 23289 名同性别成年双胞胎个体的队列研究。在 676 名双胞胎个体的子样本中研究了尼古丁依赖。
根据自我报告,受试者被分为四类:晨型、有点晨型、有点晚型、晚型(1981 年)。吸烟状况定义为当前和曾经吸烟(1975 年、1981 年和 1990 年)。ND 通过 DSM-IV 和尼古丁依赖 Fagerström 测试(FTND)(2001-05 年)进行测量。结果:与晨型相比,两性的晚型更有可能是当前吸烟者(OR=2.91,95%CI 2.50,3.38)和终身吸烟者(OR=2.67,95%CI 2.96,4.07)。晚型更不可能戒烟。用 DSM-IV 标准评估的尼古丁依赖风险在晚型中更高(OR=2.78,95%CI 1.64,4.72)。FTND 上,晚型比晨型高 0.59(95%CI 0.01,1.17)分。调整潜在混杂因素后,这些关联并未改变。
作为晚型,与当前吸烟者、对香烟依赖性更高以及戒烟可能性较低的风险独立相关。了解这些关联的原因可能阐明烟草成瘾的原因。