Luglio Gaetano, Nelson Heidi
Department of General, Oncological and Minimally-Invasive Surgery--Surgical Coloproctology Unit, Federico II University, Via Pansini 5, Naples, Italy.
Surg Oncol Clin N Am. 2010 Oct;19(4):777-91. doi: 10.1016/j.soc.2010.07.003.
As a result of several years of trials and investigations, laparoscopic colectomy for colon cancer is now considered an acceptable and safe alternative to traditional open techniques. Four large randomized trials (Barcelona, COST, COLOR, CLASSIC) have shown the noninferiority of laparoscopic colectomy in overall survival, disease-free survival, and overall and local recurrences. Laparoscopic surgery is associated with better short-term outcomes, such as shorter hospital stay, shorter duration of ileus, less narcotic usefulness and postoperative pain, and a faster postoperative recovery. The procedures are also safe and feasible in elderly patients. Hand-assisted laparoscopic colectomy is a recent hybrid technique that could reduce learning time, and its role has been established in more challenging procedures. Future prospects include robotic and natural-orifice surgery.
经过数年的试验和研究,目前认为腹腔镜结肠癌切除术是传统开放手术可接受且安全的替代方案。四项大型随机试验(巴塞罗那试验、COST试验、COLOR试验、CLASSIC试验)已表明,腹腔镜结肠癌切除术在总生存率、无病生存率以及总体和局部复发方面并不逊色。腹腔镜手术具有更好的短期效果,如住院时间更短、肠梗阻持续时间更短、麻醉药物使用更少、术后疼痛更轻以及术后恢复更快。这些手术在老年患者中也是安全可行的。手辅助腹腔镜结肠切除术是一种最新的混合技术,可缩短学习时间,其作用已在更具挑战性的手术中得到确立。未来的前景包括机器人手术和经自然腔道手术。