Department of Radiology, Medical University of Vienna, Waehringer Guertel, 18-20, 1090, Vienna, Austria.
Eur Radiol. 2011 Mar;21(3):653-62. doi: 10.1007/s00330-010-1953-x. Epub 2010 Oct 3.
To compare the diagnostic accuracy of a standard bi-directional, three-dimensional (3D) CT colonography (CTC) fly-through (standard view, SV) with a unidirectional, 3D unfolding technique (panoramic view, PV).
150 consecutive endoscopically-validated CTC patient datasets were retrospectively reviewed twice by two expert radiologists: first, with bidirectional SV, second, after 6-15 months, with unidirectional PV. Per-polyp sensitivities, percentage of visualised colonic mucosa, and reading times were calculated for both 3D visualisations. Results were tested for statistical significance by equivalence analysis for paired proportions and Student's paired t-test.
In 81 patients, 236 polyps (101 adenomas, 135 non-adenomas) were detected. Sensitivities for polyps ≤5 mm, 6-9 mm and ≥10 mm were 60.1% (113/188), 92.9% (26/28) and 95.0% (19/20) with bidirectional SV, and 60.6% (114/188), 96.4% (27/28) and 95.0% (19/20) with unidirectional PV. Overall sensitivity for adenomas was 86.1% and 84.2% for SV and PV. Both methods provided equivalent polyp detection, with an equivalence limit set at 5%. PV and SV visualised 98.9 ± 1.1% (97.0-99.9%) and 96.2 ± 2.3% (91.4-98.8%) of the colonic mucosa (p > 0.05). Mean interpretation time decreased from 14.6 ± 2.5 (9.2-22.8) minutes with SV to 7.5 ± 3.2 (5.0-14.4) using PV (p < 0.0001).
3D CTC interpretation using unidirectional PV is equally as accurate, but significantly faster than an interpretation based on bidirectional SV.
比较标准双向、三维（3D）CT 结肠成像（CTC）飞行模式（标准视图，SV）与单向、3D 展开技术（全景视图，PV）的诊断准确性。
回顾性分析 150 例经内镜验证的 CTC 患者数据集，由两名专家放射科医生进行两次阅读：第一次使用双向 SV，第二次在 6-15 个月后使用单向 PV。计算两种 3D 可视化方法的每息肉敏感度、可视结肠黏膜百分比和阅读时间。通过等效性分析和学生配对 t 检验对结果进行统计学意义检验。
在 81 例患者中，检测到 236 个息肉（101 个腺瘤，135 个非腺瘤）。对于直径≤5mm、6-9mm 和≥10mm 的息肉，双向 SV 的敏感度分别为 60.1%（113/188）、92.9%（26/28）和 95.0%（19/20），单向 PV 的敏感度分别为 60.6%（114/188）、96.4%（27/28）和 95.0%（19/20）。腺瘤的总体敏感度为 86.1%和 SV、PV 分别为 84.2%。两种方法的息肉检出率均等效，等效限设为 5%。PV 和 SV 分别可视化了 98.9±1.1%（97.0-99.9%）和 96.2±2.3%（91.4-98.8%）的结肠黏膜（p>0.05）。使用 SV 的平均解释时间为 14.6±2.5（9.2-22.8）分钟，而使用 PV 则为 7.5±3.2（5.0-14.4）分钟（p<0.0001）。
与基于双向 SV 的解释相比，使用单向 PV 的 3D CTC 解释同样准确，但速度明显更快。
