Sleep Laboratory, Pneumonology Unit, Hospital Alemán, Buenos Aires, Argentina.
Sleep Breath. 2011 Dec;15(4):679-86. doi: 10.1007/s11325-010-0421-9. Epub 2010 Oct 3.
The purpose of this study was to compare the performance of the automated detection versus the manual scoring from the ApneaLink™ device to diagnose obstructive sleep apnoea syndrome (OSAS).
All participants (96) performed the ApneaLink™ (AL) and polysomnography (PSG) simultaneously in the sleep laboratory. The two recordings were interpreted blindly. The hypopnoea criterion used for the analysis of both automatic and manual ApneaLink™ was a fall in airflow ≥50% of baseline for ≥10 s. The agreement between AL and PSG and the interobserver concordance was calculated. ROC analysis, sensitivity and specificity were assessed for the different ApneaLink™ and OSAS criteria.
Ninety patients were included (69 men; mean age, 49.6; median RDI, 13.9; median BMI, 29.3 kg/m(2)). The automatic apnoea/hypopnoea index (AHI-a) showed a lower agreement with the respiratory disturbance index (RDI) than the manual apnoea/hypopnoea (AHI-m) [AHI-a/RDI: intraclass correlation coefficient (ICC) 0.88 versus AHI-m/RDI: ICC 0.91]. The manual scoring (MS) showed a similar sensitivity and a higher specificity than the automatic scoring (AA) for the detection of OSAS, defined as an RDI ≥ 5 (sensitivity and specificity AA and MS: 89%/89%, 60%/86.7%, respectively). The accuracy of the automatic and manual scoring of the AL was similar when OSAS was defined as an RDI ≥ 20 or 30. The ApneaLink™ manual scoring had a very good interobserver agreement (k = 0.86).
The manual scoring of an ApneaLink™ recording was better than the automatic scoring in terms of agreement with RDI and to discriminate patients with OSAS. The hand scoring did not improve the accuracy of automatic scoring in patients with severe OSAS.
本研究旨在比较自动检测与 ApneaLink™ 设备的手动评分在诊断阻塞性睡眠呼吸暂停综合征(OSAS)方面的性能。
所有参与者(96 人)均在睡眠实验室同时进行 ApneaLink™(AL)和多导睡眠图(PSG)记录。两次记录均进行盲法解读。自动和手动 ApneaLink™ 分析中使用的低通气标准为气流下降≥基线的 50%,持续时间≥10 秒。计算了 AL 与 PSG 的一致性以及观察者间的一致性。评估了不同 ApneaLink™ 和 OSAS 标准的 ROC 分析、敏感性和特异性。
共纳入 90 例患者(69 例男性;平均年龄 49.6 岁;中位 RDI 为 13.9;中位 BMI 为 29.3kg/m2)。自动呼吸暂停/低通气指数(AHI-a)与呼吸紊乱指数(RDI)的一致性低于手动呼吸暂停/低通气(AHI-m)[AHI-a/RDI:组内相关系数(ICC)为 0.88 比 AHI-m/RDI:ICC 为 0.91]。与自动评分(AA)相比,手动评分(MS)对 OSAS 的检测具有相似的敏感性和更高的特异性,定义为 RDI≥5(敏感性和特异性 AA 和 MS:89%/89%,60%/86.7%)。当 OSAS 定义为 RDI≥20 或 30 时,自动和手动评分的 ApneaLink™ 准确性相似。ApneaLink™ 手动评分具有很好的观察者间一致性(k=0.86)。
在与 RDI 的一致性和区分 OSAS 患者方面,ApneaLink™ 记录的手动评分优于自动评分。在严重 OSAS 患者中,手动评分并不能提高自动评分的准确性。