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偏头痛患者血小板中的单胺氧化酶活性。

Monoamine oxidase activity in blood platelets of migraine patients.

作者信息

Caramona M M, Cotrim M D, Ribeiro C F, Macedo T

机构信息

Laboratório de Farmacologia, Faculdade de Farmácia, Coimbra, Portugal.

出版信息

J Neural Transm Suppl. 1990;32:161-4. doi: 10.1007/978-3-7091-9113-2_23.

Abstract

Biochemical changes in platelets of migraine patients during the attacks have been reported before, however there are some conflicting results. In an attempt to define the biochemical lesion in the platelets, we have carried out a survey of platelets monoamine oxidase in migraine patients with and without aura. Platelet MAO activity in platelets from migraine patients was significantly reduced when compared with normal platelets.

摘要

此前已有报道称偏头痛患者发作期间血小板会发生生化变化,然而结果存在一些矛盾之处。为了明确血小板中的生化损伤,我们对有先兆和无先兆的偏头痛患者的血小板单胺氧化酶进行了一项调查。与正常血小板相比,偏头痛患者血小板中的血小板单胺氧化酶活性显著降低。

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