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[住院婴儿下呼吸道急性感染的病因学。3. 沙眼衣原体调查]

[Etiology of lower acute respiratory infections in hospitalized infants. 3. Investigation of Chlamydia trachomatis].

作者信息

León A, Ceruti E, Díaz A, Pinto R, Farías P

机构信息

Departamento de Pediatría, Hospital Roberto del Río.

出版信息

Rev Chil Pediatr. 1990 Sep-Oct;61(5):242-7.

PMID:2089490
Abstract

Five infants with Chlamydia trachomatis associated pneumonia are analyzed. They were diagnosed out of 80 infants admitted to the hospital with pneumonia whose etiology was studied for virus, bacteria and Chlamydia trachomatis. Serum IgM antibodies to Chlamydia tr. were measured by indirect immunofluorescence (IIF), which is considered to be specific in high titers (1 greater than or equal to 32). The five cases represented 10.4% of infants studied younger than six months. One child was born by cesarean section suggesting the possibility of other non oculogenital still undefined mechanism of transmission. Clinical symptoms and laboratory findings were characteristics of those described in Chlamydia tr. pneumonia. Chlamydia trachomatis must be considered an etiologic agent in infantile pneumonia specially in the first six months of life. The high specificity and sensitivity of the IFF makes this serologic test the best non-invasive method for diagnosis of Chlamydia tr. pneumonia currently available.

摘要

对5例沙眼衣原体相关性肺炎患儿进行了分析。他们是从80例因肺炎入院的患儿中诊断出来的,这些患儿的病因研究包括病毒、细菌和沙眼衣原体。采用间接免疫荧光法(IIF)检测沙眼衣原体血清IgM抗体,高滴度(≥32)时被认为具有特异性。这5例患儿占6个月以下研究患儿的10.4%。1例患儿为剖宫产出生,提示可能存在其他非眼-生殖器途径且尚未明确的传播机制。临床症状和实验室检查结果具有沙眼衣原体肺炎所描述的特征。沙眼衣原体必须被视为婴儿肺炎的病原体,尤其是在出生后的前6个月。间接免疫荧光法的高特异性和敏感性使其成为目前诊断沙眼衣原体肺炎的最佳非侵入性血清学检测方法。

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