病毒与疾病的警示故事。
A cautionary tale of virus and disease.
机构信息
Division of Infection and Immunity, University College London, 46 Cleveland Street, London W1T 4JF, UK.
出版信息
BMC Biol. 2010 Sep 27;8:124. doi: 10.1186/1741-7007-8-124.
Abstract
The recent identification of the gammaretrovirus XMRV and a second gammaretrovirus of a different subtype in chronic fatigue syndrome has aroused much interest, not least among sufferers. However, it remains highly controversial whether the detection of these viruses represents true infection or laboratory artifacts.
摘要
最近在慢性疲劳综合征中发现了伽马逆转录病毒 XMRV 和另一种不同亚型的第二种伽马逆转录病毒，这引起了很大的兴趣，尤其是在患者中。然而，这些病毒的检测是否代表真正的感染或实验室假象仍然存在很大争议。
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2
Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States.在美国慢性疲劳综合征患者和健康对照者中未发现嗜异性鼠白血病病毒相关病毒感染的证据。
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3
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Human RNA "rumor" viruses: the search for novel human retroviruses in chronic disease.人类RNA“谣言”病毒：在慢性疾病中寻找新型人类逆转录病毒
Microbiol Mol Biol Rev. 2008 Mar;72(1):157-96, table of contents. doi: 10.1128/MMBR.00033-07.
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