School of Medicine, University of California, San Diego, California, USA.
Am J Med. 2010 Oct;123(10):885-91. doi: 10.1016/j.amjmed.2010.02.029.
This article presents a case report of nonhepatic hyperammonemia, i.e., elevated serum ammonia secondary to a nonhepatic etiology. It then discusses the importance of broadening one's differential diagnosis to include such nonhepatic causes of elevated ammonia levels, and provides a short review of rarer causes of hyperammonemia in the adult population. Treating the underlying condition is the best way to prevent recurrence of hyperammonemia. However, symptomatic treatment should not be delayed while investigating the underlying source.
这篇文章报告了一例非肝性高血氨症病例,即继发于非肝脏病因的血清氨升高。然后讨论了拓宽鉴别诊断范围以包括此类非肝脏性高氨血症病因的重要性,并简要回顾了成人中较少见的高氨血症病因。治疗基础疾病是预防高氨血症复发的最佳方法。然而,在调查潜在病因的同时,不应延迟对症治疗。