Department of Pediatric Surgery, Baragwanath Hospital, University of the Witwatersrand, PO Box 2648, Parklands 2121, South Africa.
J Pediatr Surg. 2010 Oct;45(10):2068-70. doi: 10.1016/j.jpedsurg.2010.06.026.
We report 2 human immunodeficiency virus-positive patients with refractory esophageal strictures secondary to candidiasis. They presented with progressive dysphagia and had suffered from oropharyngeal and/or esophageal candidiasis within the preceding 3 months. Both failed conservative management of these strictures, including systemic antifungal therapy, administration of proton pump inhibitors, and numerous attempts at stricture dilation, ultimately progressing to open transhiatal esophagectomy. Although challenging in the immunocompromised host, successful treatment of these strictures by gastric interposition is achievable with minimal morbidity.
我们报告了 2 例人类免疫缺陷病毒阳性患者，他们因念珠菌病而出现难治性食管狭窄。他们表现为进行性吞咽困难，并在之前 3 个月内患有口咽和/或食管念珠菌病。这 2 例患者均经保守治疗（包括全身抗真菌治疗、质子泵抑制剂治疗和多次尝试扩张狭窄）后食管狭窄仍未缓解，最终行开放性经食管裂孔食管切除术。尽管在免疫功能低下的宿主中具有挑战性，但通过胃间置术成功治疗这些狭窄可实现最小的发病率。
