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减重手术的胆道并发症风险。

Risk of biliary complications in bariatric surgery.

机构信息

Unité deChirurgie Viscérale, Endocrinienne et Métabolique, Centre Hospitalier d'Arras, Boulevard Besnier, BP914, 62022 Arras cedex, France.

出版信息

J Visc Surg. 2010 Aug;147(4):e217-20. doi: 10.1016/j.jviscsurg.2010.08.001.

DOI:10.1016/j.jviscsurg.2010.08.001
PMID:20920904
Abstract

Gallstones are commonly observed after rapid weight loss, particularly after bariatric surgery. Preventive measures of gallstone formation and potential related complications are still debated. This study aimed to propose a standardized strategy according to the results of the literature. Thus, preventive measures should be determined according to patient status (evaluated clinically and by routine ultrasound) and the type of bariatric surgery. Cholecystectomy should be performed in patients with symptomatic gallstones irrespective of the planned operation, or for asymptomatic gallstones during a gastric by-pass. In other settings, ursodesoxycholic acid should be given postoperatively for 6 months.

摘要

胆结石在快速减肥后很常见,尤其是在接受减重手术后。对于胆结石形成的预防措施和潜在相关并发症仍存在争议。本研究旨在根据文献结果提出一种标准化策略。因此,预防措施应根据患者的情况(通过临床评估和常规超声检查评估)和减重手术的类型来确定。对于有症状的胆结石患者,无论计划进行何种手术,均应进行胆囊切除术;对于胃旁路术后无症状的胆结石患者,也应进行胆囊切除术。在其他情况下,应在术后给予熊去氧胆酸治疗 6 个月。

相似文献

1
Risk of biliary complications in bariatric surgery.减重手术的胆道并发症风险。
J Visc Surg. 2010 Aug;147(4):e217-20. doi: 10.1016/j.jviscsurg.2010.08.001.
2
Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after bariatric surgery: study protocol for a randomized controlled trial (UPGRADE trial).熊去氧胆酸预防减重手术后有症状胆结石疾病:一项随机对照试验的研究方案(UPGRADE试验)
BMC Gastroenterol. 2017 Dec 20;17(1):164. doi: 10.1186/s12876-017-0674-x.
3
Incidence of symptomatic gallstones after gastric bypass: is prophylactic treatment really necessary?胃旁路术后有症状胆结石的发生率:预防性治疗真的有必要吗?
Surg Obes Relat Dis. 2005 Nov-Dec;1(6):564-7; discussion 567-8. doi: 10.1016/j.soard.2005.08.004.
4
Patients developed symptomatic gallstones between 3 and 21 months after Roux-en-Y gastric bypass (RYGB), neither prophylactic cholecystectomy nor treatment with ursodeoxycholic acid is necessary after open RYGB.患者在Roux-en-Y胃旁路术(RYGB)后3至21个月出现有症状的胆结石,开腹RYGB术后既不需要预防性胆囊切除术,也不需要用熊去氧胆酸治疗。
Surg Obes Relat Dis. 2006 Mar-Apr;2(2):233; author reply 233. doi: 10.1016/j.soard.2006.01.011.
5
Elective cholecystectomy after Roux-en-Y gastric bypass: why should asymptomatic gallstones be treated differently in morbidly obese patients?Roux-en-Y胃旁路术后择期胆囊切除术:为什么病态肥胖患者的无症状胆结石应区别对待?
Surg Obes Relat Dis. 2005 Nov-Dec;1(6):555-60. doi: 10.1016/j.soard.2005.08.002. Epub 2005 Sep 28.
6
[Gallbladder complications after bariatric surgery].[减肥手术后的胆囊并发症]
Gastroenterol Clin Biol. 2007 Apr;31(4):378-84. doi: 10.1016/s0399-8320(07)89396-1.
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Gallstone disease: Primary and secondary prevention.胆结石病:一级预防和二级预防
Best Pract Res Clin Gastroenterol. 2006;20(6):1063-73. doi: 10.1016/j.bpg.2006.03.008.
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[Gallstones following considerable weight loss and recommendations for their prevention].
Ned Tijdschr Geneeskd. 2004 Jan 24;148(4):174-7.
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Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after bariatric surgery (UPGRADE): a multicentre, double-blind, randomised, placebo-controlled superiority trial.熊去氧胆酸预防减肥手术后症状性胆石病(UPGRADE):一项多中心、双盲、随机、安慰剂对照优效试验。
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Gallstone formation prophylaxis after gastric restrictive procedures for weight loss: a randomized double-blind placebo-controlled trial.减肥胃限制性手术后胆结石形成的预防:一项随机双盲安慰剂对照试验。
Ann Surg. 2003 Nov;238(5):697-702. doi: 10.1097/01.sla.0000094305.77843.cf.

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Cholelithiasis, Gut Microbiota and Bile Acids after Bariatric Surgery-Can Cholelithiasis Be Prevented by Modulating the Microbiota? A Literature Review.胆石病、肠道微生物群和减肥手术后的胆汁酸-通过调节微生物群可以预防胆石病吗?文献综述。
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Biliary complications associated with weight loss, cholelithiasis and choledocholithiasis.
与体重减轻、胆结石和胆总管结石相关的胆道并发症。
World J Gastrointest Pharmacol Ther. 2024 Jul 5;15(4):95647. doi: 10.4292/wjgpt.v15.i4.95647.
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Role of Ursodeoxycholic Acid in the Prevention of Gallstones Formation in Bariatric Patients-a Systematic Review and Meta-Analysis of Randomised Trials.熊去氧胆酸在预防肥胖症患者胆石形成中的作用:一项随机试验的系统评价和荟萃分析。
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