Department of Surgery, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Department College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Saudi J Gastroenterol. 2020 Mar-Apr;26(2):94-98. doi: 10.4103/sjg.SJG_472_19.
BACKGROUND/AIM: The worldwide prevalence of obesity has increased dramatically over the past years. In the Arab region, 66%-75% of adults and 25%-40% of children are either overweight or obese. Bariatric surgery has become the most effective approach for managing obesity and its co-morbidities. An expected outcome of bariatric surgery is cholelithiasis, which is one of the established risk factors of rapid weight loss. The aim of this study is to detect the incidence of symptomatic cholelithiasis among bariatric patients.
A retrospective cohort study on 711 patients aged between 18 and 60 who underwent laparoscopic sleeve gastrectomy (LSG) was conducted at King Saud University Medical City from January 2016 to January 2018.
The postoperative incidence of symptomatic cholelithiasis was 3.5%. The mean duration of symptom development was 12.4 months. The rates of weight loss at 6 and 12 months for patients with symptomatic cholelithiasis were 28.94 ± 4.89% and 38.51 ± 6.84%, respectively (P = 0.002), which were significantly higher than in patients without symptomatic cholelithiasis during the same follow-up period (24.41 ± 6.6% and 32.29 ± 10.28%), respectively; (P = 0.012).
We found a 3.5% incidence of symptomatic cholelithiasis among post-LSG patients in a period of 2 years. Rapid weight loss was the only risk factor that contributed to the development of post-LSG gallbladder disease.
Results were expressed as absolute numbers and percentages for categorical variables and as mean and standard deviation for continuous variables. A paired sample t-test was performed to determine significant differences between means at different time stamps. Statistical analysis was performed using the Statistical Package for the Social Sciences (SPSS) version 23.0.
背景/目的：近年来，全球肥胖患病率显著增加。在阿拉伯地区，66%-75%的成年人和 25%-40%的儿童超重或肥胖。减重手术已成为治疗肥胖及其合并症的最有效方法。减重手术后发生胆石症是可以预期的结果，胆石症是快速减重的既定风险因素之一。本研究旨在检测减重患者中胆石症的发生率。
对 2016 年 1 月至 2018 年 1 月在沙特国王大学医学城接受腹腔镜袖状胃切除术（LSG）的 711 例年龄在 18 至 60 岁之间的患者进行了回顾性队列研究。
术后有症状胆石症的发生率为 3.5%。症状发展的平均持续时间为 12.4 个月。有症状胆石症患者的体重减轻率在 6 个月和 12 个月时分别为 28.94±4.89%和 38.51±6.84%（P=0.002），显著高于同一随访期间无症状胆石症患者（分别为 24.41±6.6%和 32.29±10.28%）（P=0.012）。
我们发现，在 2 年的时间内，LSG 术后患者有 3.5%的有症状胆石症发生率。快速减肥是导致 LSG 后胆囊疾病发展的唯一危险因素。
分类变量的结果表示为绝对数和百分比，连续变量表示为均值和标准差。采用配对样本 t 检验比较不同时间点均值的差异。统计分析使用社会科学统计软件包（SPSS）版本 23.0 进行。
