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痴呆症中精神病的测量:评估工具的比较。

The measurement of psychosis in dementia: a comparison of assessment tools.

机构信息

The Herczeg Institute on Aging, Department of Health Promotion, Sackler Faculty of Medicine, School of Public Health, Tel-Aviv University, Tel-Aviv, Israel.

出版信息

Alzheimer Dis Assoc Disord. 2011 Apr-Jun;25(2):101-8. doi: 10.1097/WAD.0b013e3181f811f4.

Abstract

The precise operational definition of psychosis in dementia lacks consensus, partially owing to incongruence in the various assessment tools used. This study compares assessments of psychotic symptoms in persons with dementia, specifically of hallucinations and delusions, through the 4 most frequently used assessments. Participants were 74 nursing home residents from 9 nursing homes in Israel, diagnosed with dementia. Assessment tools used included the Behavioral Pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD), the Neuropsychiatric Inventory-Nursing Homes (NPI-NH), the Consortium to Establish a Registry for Alzheimer's Disease Behavior Rating Scale for Dementia (CERAD-BRSD), and the Columbia University Scale for Psychopathology in Alzheimer's Disease (CUSPAD). The highest prevalence rates of delusions were found through the CUSPAD, and the lowest through the CERAD-BRSD. Rates identified by the BEHAVE-AD were intermediate and similar to those of the NPI-NH. As for hallucinations, rates indicated by the BEHAVE-AD, the NPI-NH, and the CUSPAD were similar, with small sample-based differences, and higher than those found through the CERAD-BRSD. The CERAD-BRSD, soliciting reports of the fewest specific symptoms, detected the fewest psychotic symptoms. The CUSPAD, soliciting the most items, presented the highest prevalence rates. The BEHAVE-AD and the NPI-NH had similar rates and showed a high convergent validity.

摘要

痴呆患者精神病的精确操作性定义尚未达成共识,部分原因是使用的各种评估工具不一致。本研究通过 4 种最常用的评估工具比较了痴呆患者(尤其是幻觉和妄想)的精神病症状评估。参与者是来自以色列 9 家养老院的 74 名养老院居民,被诊断为痴呆症。使用的评估工具包括:阿尔茨海默病行为病理评定量表(BEHAVE-AD)、神经精神科住院患者护理评估量表(NPI-NH)、阿尔茨海默病建立注册研究用精神病行为评定量表(CERAD-BRSD)和哥伦比亚大学阿尔茨海默病精神病评定量表(CUSPAD)。通过 CUSPAD 发现妄想的患病率最高,而通过 CERAD-BRSD 发现的患病率最低。BEHAVE-AD 确定的比率处于中间水平,与 NPI-NH 相似。至于幻觉,BEHAVE-AD、NPI-NH 和 CUSPAD 指示的比率相似,基于样本的差异较小,高于 CERAD-BRSD 发现的比率。CERAD-BRSD 征集的特定症状最少,检测到的精神病症状最少。CUSPAD 征集的项目最多,呈现出最高的患病率。BEHAVE-AD 和 NPI-NH 具有相似的比率,并显示出较高的一致性。

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