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微创全胃切除术治疗胃癌:初步系列研究。

Minimally invasive total gastrectomy for gastric cancer: a pilot series.

机构信息

Department of General & Oncologic Surgery, City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA.

出版信息

J Gastrointest Surg. 2011 Jan;15(1):81-6. doi: 10.1007/s11605-010-1356-y. Epub 2010 Oct 5.

Abstract

BACKGROUND

Minimally invasive surgery for select gastrointestinal disease has gained worldwide acceptance. However, laparoscopic total gastrectomy for cancer remains controversial. The purpose of this study was to examine an initial experience with laparoscopic total gastrectomy.

METHODS

Medical records of 16 consecutive patients who underwent laparoscopic total gastrectomy between September 2007 and December 2009 were reviewed in a retrospective manner. Esophagojejunostomy was completed using a transorally delivered anvil, with double-stapled esophageal anastomosis.

RESULTS

There were no conversions to open procedures. Two patients (12.5%) required extended resections with en bloc distal pancreatectomy and splenectomy, one of whom also underwent transverse colectomy. The median lymph node count for patients who underwent D2 lymphadenectomy (n = 12) for gastric adenocarcinoma was 31. There were no perioperative deaths and the median length of stay was 8 days. There were no anastomotic leaks, but three patients developed anastomotic strictures amenable to dilatation.

CONCLUSIONS

Minimally invasive total gastrectomy can be performed safely and with adequate lymphadenectomy. The procedure provides an excellent short-term outcome with potential for improved patient outcome.

摘要

背景

微创外科治疗胃肠道疾病已得到全球认可。然而,腹腔镜全胃切除术治疗癌症仍存在争议。本研究旨在探讨腹腔镜全胃切除术的初步经验。

方法

回顾性分析 2007 年 9 月至 2009 年 12 月连续 16 例接受腹腔镜全胃切除术患者的病历资料。采用经口导入的钉砧行食管空肠吻合术,并用双吻合器行食管吻合。

结果

无中转开腹手术。2 例(12.5%)患者需要扩大切除,联合进行远端胰腺和脾切除术,其中 1 例还进行了横结肠切除术。行 D2 淋巴结清扫术(n=12)的胃腺癌患者的中位淋巴结计数为 31 枚。无围手术期死亡病例,中位住院时间为 8 天。无吻合口漏,但 3 例患者发生吻合口狭窄,可进行扩张治疗。

结论

微创全胃切除术安全可行,且能进行充分的淋巴结清扫。该手术具有良好的短期效果,可能改善患者的预后。

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