Noma Yoshiaki, Asakawa Yoshinori
Faculty of Human Life Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
Nat Prod Commun. 2010 Sep;5(9):1339-41.
The biotransformation of (-)-nopol benzyl ether (5) by Aspergillus niger TBUYN-2 and A. niger Tiegh CBSYN was investigated. A. niger biotransformed 5 to afford (-)-4-oxonopol-2',4'-dihydroxybenzyl ether (6), and (-)-4-oxonopol (7) as main products. Compound 6 showed strong antioxidant activity (IC50 30.2 microM), which was very similar to that of butyl hydroxyl anisol (BHA).
