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黑尿和皮肤变黑病例——甲酚中毒。

A case of black urine and dark skin - cresol poisoning.

机构信息

College of Medicine, International Medical University, Kuala Lumpur, Malyasia.

出版信息

Clin Toxicol (Phila). 2010 Nov;48(9):959-60. doi: 10.3109/15563650.2010.523830. Epub 2010 Oct 6.

DOI:10.3109/15563650.2010.523830
PMID:20923396
Abstract

INTRODUCTION

Cresol is a phenol derivative used as a disinfectant worldwide. Acute cresol poisoning is potentially fatal as it may cause multiple organ failure. We present a case of acute cresol intoxication in a male patient to illustrate the effects of cresol poisoning.

CASE

A 42-year-old male presented with black urine, painless brownish dermal burns, and a strong carbolic acid odor. The patient was immediately resuscitated with adequate oxygenation and aggressive fluid resuscitation. He was subsequently admitted to the intensive care unit, where his treatment course was complicated by pneumonia, gastrointestinal bleeding, hepatic dysfunction, and acute renal failure. After receiving supportive intensive care, the patient recovered and was discharged with no sequelae.

CONCLUSION

The distinctive clinical features of this case may be useful in diagnosis, because laboratory analytical methods for cresols are not routinely available at most hospitals.

摘要

简介

甲酚是一种酚类衍生物,被广泛用作消毒剂。急性甲酚中毒可能导致多器官衰竭,具有潜在致命性。我们报告了 1 例急性甲酚中毒的男性患者病例,以阐明甲酚中毒的影响。

病例

一名 42 岁男性因黑尿、无痛性棕褐色皮肤烧伤和强烈的石碳酸气味就诊。立即给予患者充分的氧合和积极的液体复苏。随后,他被收入重症监护病房,在那里他的治疗过程中并发肺炎、胃肠道出血、肝功能障碍和急性肾衰竭。在接受支持性重症监护治疗后,患者康复出院,无后遗症。

结论

该病例的独特临床特征可能有助于诊断,因为大多数医院通常没有常规的甲酚实验室分析方法。

相似文献

1
A case of black urine and dark skin - cresol poisoning.黑尿和皮肤变黑病例——甲酚中毒。
Clin Toxicol (Phila). 2010 Nov;48(9):959-60. doi: 10.3109/15563650.2010.523830. Epub 2010 Oct 6.
2
Concentrated cresol intoxication.浓甲酚中毒。
Vet Hum Toxicol. 1998 Dec;40(6):341-3.
3
Determination of phenol and o-cresol by GC/MS in a fatal poisoning case.气相色谱/质谱联用仪测定一起致命中毒案件中的苯酚和邻甲酚
Forensic Sci Int. 2004 Jan 28;139(2-3):191-4. doi: 10.1016/j.forsciint.2003.10.023.
4
A fatal case of saponated cresol ingestion.一例因摄入皂化甲酚致死的病例。
Soud Lek. 2006 Jul;51(3):47-50.
5
[Fatal transcutaneous resorption of Lysol].[来苏儿经皮肤吸收致死]
Sud Med Ekspert. 1991 Jan-Mar;34(1):48-50.
6
[About a cresol intoxication].[关于甲酚中毒]
Rev Med Brux. 2018;39(3):150-154. doi: 10.30637/2018.17-020. Epub 2018 May 30.
7
Acute respiratory distress syndrome following cutaneous exposure to Lysol: a case report.皮肤接触来苏尔后发生急性呼吸窘迫综合征:一例报告
Zhonghua Yi Xue Za Zhi (Taipei). 1999 Dec;62(12):901-6.
8
Severe ARDS Complicating an Acute Intentional Cresol Poisoning.严重急性呼吸窘迫综合征并发急性故意性甲酚中毒
Case Rep Crit Care. 2019 Aug 20;2019:6756352. doi: 10.1155/2019/6756352. eCollection 2019.
9
An autopsy case of poisoning by massive absorption of cresol a short time before death.一例生前短时间内大量吸收甲酚中毒的尸检病例。
Forensic Sci Int. 2002 Mar 28;126(1):77-81. doi: 10.1016/s0379-0738(02)00024-5.
10
Autopsy report for chemical burns from cresol solution.甲酚溶液化学烧伤尸检报告
Exp Toxicol Pathol. 2016 Jan;68(1):99-102. doi: 10.1016/j.etp.2015.09.005. Epub 2015 Sep 26.

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